金莲花抑菌抗病毒活性成分的初步研究  

Study on the antibacterial and antiviral activity compositions of Trollius chinensis Bunge.

作　　者：林秋凤[1] 冯顺卿[1] 李药兰[1] 岑颖洲[1] 杨宜婷[1] 王凌云[1] 

机构地区：[1]暨南大学化学系,广东广州510632

出　　处：《浙江大学学报（理学版）》2004年第4期412-415,共4页Journal of Zhejiang University（Science Edition）

基　　金：广东省中医药管理局资助项目(100064);国家自然科学基金资助项目(20172020);省自然科学基金资助项目(粤科基(2001)10号-010401).

摘　　要：用柱层析等色谱分离手段从金莲花中得到3个纯化合物,通过UV、IR、1H-NMR等现代波谱技术分别鉴定为原金莲酸、牡荆甙和荭草甙.对上述化合物和所提取的总黄酮样品进行抑菌、抗病毒活性研究.结果表明,总黄酮、牡荆甙和荭草甙对金黄色葡萄球菌和表皮葡萄球菌有很好的抑制效果,并对副流感病毒有强的抑制作用.该项研究是由本实验室首次报道.Proglobeflowery acid, orientin, vitexin were isolated from the n-butanol extract of Trollius chinensis Bunge. The antibacterial and antiviral activities against some bacteria and virus were investigated. The results showed that the total flavones, orientin, vitexin exhibited antibacterial activities in various degrees against the bacteria; proglobeflowery acid exhibited antivirus activity against Flu A virus, orientin and vitexin showed evident antivirus activities against para3 virus. This research was first done by our lab.

关 键 词：金莲花 原金莲酸 牡荆甙 荭草甙 抑菌 抗病毒 

分 类 号：O629.5[理学—有机化学]