55例多原发恶性肿瘤回顾性临床分析  

Retrospective Clinical Analysis of 55 Cases of Multiple Primary Malignant Tumors

作　　者：张云波[1] 张建光[1] 刘俊启[2] 郑丽萍[1] 

机构地区：[1]淄博万杰肿瘤医院肿瘤科,山东 淄博 [2]郑州大学第一附属医院放疗科,河南 郑州

出　　处：《临床医学进展》2019年第11期1238-1242,共5页Advances in Clinical Medicine

基　　金：国家自然科学基金资助项目(81703158).

摘　　要：目的:探讨多原发恶性肿瘤的发病情况、临床特点及与生存率之间的相关性。方法:收集我院2014年7月~2019年5月收治865例患者,其中55例为双原发或三原发恶性肿瘤,分析其病历资料。结果:多原发恶性肿瘤患者发病率为6.36%,其中双原发恶性肿瘤为49例,三原发恶性肿瘤为6例,发病率为0.69%。男性27例,女性28例,第一原发恶性肿瘤平均年龄54.84岁,第二原发恶性肿瘤平均年龄为62.7岁,第三原发恶性肿瘤平均年龄为64.33岁。结论:多原发恶性肿瘤以消化道多见,其次为肺癌。高发年龄为40~69岁之间。第一原发恶性肿瘤发病年龄与生存率成正相关,相关系数为0.51。而第二原发恶性肿瘤发病年龄与生存率成明显负相关,相关系数为?0.93。Objective: To investigate correlation of the incidence, clinical characteristics and survival rate of multiple primary malignant tumors. Methods: 865 cases of malignant tumors were treated in our hospital from July 2014 to May 2019, 55 of them were double or triple primary malignant tumors, and their medical records were analyzed. Results: The incidence of multiple primary malignant tumors was 6.36%, including 49 cases of double primary malignant tumors and 6 cases of three primary malignant tumors. The incidence was 0.69%. There were 27 males and 28 females. The average age of the first primary malignant tumor was 54.84 years;the average age of the second primary malignant tumor was 62.7 years;and the average age of the third primary malignant tumor was 64.33 years. Conclusion: Digestive tract is the most common primary malignant tumor, followed by lung cancer. The high incidence age is between 40 and 69 years old. The age at onset of the first primary malignant tumor was positively correlated with survival rate. The correlation coefficient is 0.51. The age at onset of the second primary malignant tumor was negatively correlated with survival rate. The correlation coefficient is ?0.93.

关 键 词：多原发恶性肿瘤 发病年龄 生存率 

分 类 号：R73[医药卫生—肿瘤]