青年肺癌与老年肺癌的临床特征对比分析  

Comparative Analysis of the Clinical Features of Lung Cancer between Young and Old Patients

作　　者：国建林 张在先 张传玉[1] 

机构地区：[1]青岛大学附属医院放射科,山东 青岛

出　　处：《临床医学进展》2020年第7期1205-1210,共6页Advances in Clinical Medicine

摘　　要：目的:探讨青年肺癌与老年肺癌患者的临床特征。方法:选取2016年1月至2019年6月期间收治的120例≤40岁的肺癌患者作为青年组,另随机选取118例≥70岁的同期肺癌患者作为老年组,比较两组患者的临床特征。结果:青年肺癌患者以无吸烟史多见,老年肺癌患者以有吸烟史多见(P 0.05)。结论:青年肺癌女性、不吸烟者、腺癌、III^IV期临床分期患者比例较高,ALK重排阳性率较高,EGFR 19外显子突变率较高;老年肺癌吸烟者、鳞癌患者比例较高,EGFR突变率较高,临床工作中应适当参考这些特征,以做到肺癌的早期诊断及有效治疗。Objective: To explore the clinical features of lung caner in young and old patients. Methods: From January 2016 to June 2019, 120 patients (≤40 years) with lung cancer were selected as the youth group and 118 patients (≥70 years) with lung cancer were selected randomly as the elderly group during the same period. The clinical features were compared between the two groups. Results: Majority of young patients with lung cancer were non-smokers while most elderly patients were smokers (P 0.05). Conclusion: Lung cancer in young patients is connected with higher proportion of females, non-smokers, adenocarcinoma, stage III - IV, ALK gene rearrangements and EGFR exon 19 mutations. Lung cancer in old patients is connected with higher proportion of smokers, squamous carcinoma and EGFR gene mutations. We should be aware of these characteristics to achieve the early diagnosis and effective treatment of lung caner.

关 键 词：肺肿瘤 青年人 老年人 临床特征 

分 类 号：R73[医药卫生—肿瘤]