副神经节瘤最新研究进展  

Recent Research Progress of Paraganglioma

作　　者：常正松 张易青[2] 

机构地区：[1]青海大学研究生院,青海 西宁 [2]青海大学附属医院病理科,青海 西宁

出　　处：《临床医学进展》2021年第9期4048-4053,共6页Advances in Clinical Medicine

摘　　要：副神经节瘤(Paraganglioma)是一种源于胚胎时期残留在体内的神经嵴源性副神经节细胞的神经内分泌肿瘤,可发生于全身各处,但在肾上腺和颈动脉体周围多见。随着研究的进展,曾被人们视为良性的副神经节瘤现被认为是一种恶性肿瘤,其复发及转移的机制成为了研究的热点。本文旨在对副神经节瘤的分类、相关基因及治疗的研究进行复习,为未来对其的更进一步研究打下相应理论基础。Paraganglioma is a kind of neuroendocrine tumor which derived from neural crest derived paraganglion cells remaining in the body during embryonic stage. It can induce all over the body, but it is common around the adrenal gland and carotid body. With the progress of research, paraganglioma, once regarded as benign, is now considered as a malignant tumor. The mechanism of recurrence and metastasis has become a research hotspot. This paper aims to review the classification, related genes and treatment of paraganglioma, so as to lay a corresponding theoretical foundation for further research in the future.

关 键 词：副神经节瘤 嗜铬细胞瘤 SHDB SSTR2 

分 类 号：R73[医药卫生—肿瘤]