溃疡性结肠炎黏膜愈合相关血清学指标的研究现状  

Current Status of Serological Markers in Predicting Mucosal Healing in Ulcerative Colitis

作　　者：杨雪莲[1] 李航[1] 边城[2] 徐永红[1] 

机构地区：[1]青岛大学附属医院消化科,山东 青岛 [2]青岛大学附属医院感染科,山东 青岛

出　　处：《临床医学进展》2021年第11期4997-5001,共5页Advances in Clinical Medicine

摘　　要：溃疡性结肠炎(Ulcerative colitis, UC)是一种慢性非特异性肠道疾病,其主要特点是结直肠黏膜的持续性炎症反应,病情轻重不等。结肠镜检查是临床上评估UC病情及活动度的金标准。内镜下黏膜愈合(Mucosal Healing MH)作为评估UC治疗效果的指标,得到广泛认可。近年来,非侵入性血清学指标在UC黏膜愈合中的预测价值引起了诸多学者的关注,本文就目前国内外对UC黏膜愈合有关的血清学指标的研究现状做一综述。Ulcerative colitis (UC) is a chronic non-specific intestinal disease with multiple disease severity, which is characterized by the persistent inflammation of the colorectal mucosa. Colonoscopy is the gold standard for evaluating the condition and activity of patients. Endoscopic mucosal healing (Mucosal Healing MH) is widely considered as the best indicator for evaluating effect of treatment in UC. Nowadays, the value of non-invasive serological indicators to predict MH in patients with UC has acquired extensive concern. This article reviews the current research status of serological indicators, which is related to MH in patients with UC at home and abroad.

关 键 词：溃疡性结肠炎 黏膜愈合 血清胆红素 血小板 血清球蛋白 血清白蛋白 

分 类 号：R57[医药卫生—消化系统]