中枢神经系统脱髓鞘疾病与痫性发作  

Demyelinating Diseases of the Central Nervous System and Seizures

作　　者：周雪莲[1] 李秀娟[1] 

机构地区：[1]重庆医科大学附属儿童医院神经内科,儿童发育疾病研究教育部重点实验室,国家儿童健康与疾病临床医学研究中心,儿科学重庆市重点实验室,重庆

出　　处：《临床医学进展》2022年第3期2329-2333,共5页Advances in Clinical Medicine

摘　　要：中枢神经系统脱髓鞘疾病是一种以神经功能障碍为主要表现的自身免疫性疾病,常见病种包括多发性硬化、视神经脊髓炎谱系疾病、少突胶质细胞糖蛋白IgG抗体相关疾病。这类疾病以视神经炎、脊髓炎、共济失调等为主要临床表现,部分有痫性发作。近年来,越来越多的研究表明,中枢神经脱髓鞘疾病与痫性发作有关,但其痫性发作的机制尚不明确。本文旨在对常见中枢神经脱髓鞘疾病与相关痫性发作进行综述。Demyelinating diseases of the central nervous system are autoimmune diseases with neurological dysfunction as the main manifestation. Common diseases include multiple sclerosis, neuromyelitis optica spectrum disorders, anti-myelin oligodendrocyte glycoprotein-IgG associated disorders. The prominent clinical symptoms include optic neuritis, myelitis and ataxia, and seizures. In recent years, more and more studies have shown that demyelinating diseases of the central nervous system are related to seizures, but the mechanism is not clear. This paper aims to review demyelinating diseases of the central nervous system and related seizures.

关 键 词：中枢神经系统脱髓鞘疾病 痫性发作 少突胶质细胞糖蛋白IgG抗体相关疾病 

分 类 号：R744.5[医药卫生—神经病学与精神病学]