乳腺癌TILs与新辅助疗效之间相关性研究  

Research on the Correlation between TILs and Neoadjuvant Efficacy in Breast Cancer

作　　者：傅腾超 赵晓辉 牛婷婷 吴琍[2] 

机构地区：[1]青岛大学,山东 青岛 [2]青岛大学附属医院,山东 青岛

出　　处：《临床医学进展》2022年第8期7353-7359,共7页Advances in Clinical Medicine

摘　　要：乳腺癌已经成为危害女性健康最常见的恶性肿瘤之一,且发病率逐年上升,严重危害女性的生命健康。乳腺癌的生存环境不仅由肿瘤细胞组成,还包括与肿瘤相互接触的细胞,这些共同构成了肿瘤微环境,在肿瘤微环境中,肿瘤浸润淋巴细胞起到了重要作用,有研究证明,TILs与新辅助化疗的疗效相关,在不同亚型当中,TILs的作用也不尽相同,研究TILs对我们预测乳腺癌患者的预后将会产生重要意义。Breast cancer has become one of the most common malignant tumors endangering women’s health, and the incidence is increasing year by year, seriously endangering women’s life and health. Breast cancer survival environment is not only composed of tumor cells, including the contact with tumor cells. These constitute the tumor microenvironment. In tumor microenvironment, the tumor infil-trating lymphocytes play an important role. Research has shown that TILs are associated with the curative effect of neoadjuvant chemotherapy. Among different subtypes, the role of TILs is also dif-ferent. The research of TILs is of great significance for us to predict the prognosis of breast cancer patients.

关 键 词：肿瘤浸润淋巴细胞 免疫微环境 疗效 

分 类 号：R737.9[医药卫生—肿瘤]