常见自身免疫性肝病临床及病理研究进展  

Clinical and Pathological Research Progress of Common Autoimmune Liver Diseases

作　　者：丁良玉 刘贵生[2] 

机构地区：[1]西安医学院,陕西 西安 [2]陕西省人民医院消化内一科,陕西 西安

出　　处：《临床医学进展》2022年第10期8983-8989,共7页Advances in Clinical Medicine

摘　　要：自身免疫性肝病(AILD)是一类由自身免疫系统异常引起的慢性肝脏疾病。目前,临床上最常见的AILD是自身免疫性肝炎(autoimmune hepatitis, AIH)和原发性胆汁性胆管炎(primary biliary cholangitis, PBC),若不能得到及时有效的治疗,均可发展至肝硬化。AILD的临床表现多无特异性,但其生化指标、自身抗体及组织学特点可帮助进行诊断及鉴别诊断。特别是肝脏的组织病理学在对疾病的认识过程中起到越来越重要的作用。Autoimmune liver diseases (AILD) are chronic liver diseases caused by abnormal autoimmune sys-tem. At present, the most prevalent AILD are autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC). If not treated promptly and effectively, it may develop to be cirrhosis. The clinical manifestations of AILD are not specific, but their biochemical indexes, autoantibodies and histolog-ical features can help in the diagnosis and differential diagnosis. In particular, liver histopathology plays an increasingly important role in the understanding of disease.

关 键 词：自身免疫性肝病 自身免疫性肝炎 原发性胆汁性胆管炎 临床特点 病理学 

分 类 号：R575[医药卫生—消化系统]