复发性阔韧带骨外尤文氏肉瘤1例报道并文献复习  

Extraskeletal Ewing’s Sarcoma: A Case Report and Literature Review

作　　者：赵孔媛 焦今文[2] 宋冰冰 郭恩慧 王黎明[2] 

机构地区：[1]青岛大学,山东 青岛 [2]青岛大学附属医院,山东 青岛

出　　处：《临床医学进展》2022年第11期9743-9749,共7页Advances in Clinical Medicine

摘　　要：目的:探讨复发性骨外尤文氏肉瘤(EES)的疾病特征,了解其临床表现、诊断及治疗方案。方法:对1例阔韧带复发的EES患者的临床资料进行回顾性分析,复习相关文献并进行讨论。结果:该例EES患者临床表现及影像学特征缺乏特异性,确诊依赖于病理,其中免疫组化结果为CD99 (+),基因检测EWSR1基因易位,复发性EES治疗采用综合治疗,现术后放化疗中,一般状况好。结论:阔韧带EES极其罕见,具有易复发、易转移的特点,宜采取多模式联合的治疗策略,但复发和转移性尤因肉瘤的治疗仍是巨大挑战。Objective: To investigate the disease characteristics of recurrent extraskeletal Ewing’s sarcoma (EES), and to understand its clinical manifestations, diagnosis and treatment. Methods: The clinical data of one EES patient with parametrial recurrence were retrospectively analyzed, and relevant literatures were reviewed and discussed. Results: The clinical manifestations and imaging features of this EES patient lacked specificity, and the diagnosis depended on pathology. The immunohisto-chemical results were CD99 (+), and the gene detection of EWSR1 gene translocation was performed. The recurrent EES was treated with comprehensive treatment. During chemotherapy, the general condition is good. Conclusion: Parametrial EES is extremely rare, and has the characteristics of easy recurrence and metastasis. A multimodal combined treatment strategy should be adopted, but the treatment of recurrent and metastatic Ewing sarcoma is still a huge challenge.

关 键 词：阔韧带 骨外尤文氏肉瘤 临床特征 诊断 治疗 

分 类 号：R73[医药卫生—肿瘤]