非酒精性脂肪性肝病从脾虚论治的研究进展  

Research Progress on Treatment of Non-Alcoholic Fatty Liver Disease from Spleen Deficiency

作　　者：夏雪碧露 高鹏飞 胡春兰 姚绮霞 

机构地区：[1]金山区石化社区卫生服务中心,上海 [2]复旦大学附属金山医院中医科,上海

出　　处：《临床医学进展》2023年第3期4270-4278,共9页Advances in Clinical Medicine

摘　　要：非酒精性脂肪性肝病(non-alcoholic fatty liver disease, NAFLD)的发病率逐年升高,治疗上西医多采用保肝药、降脂药及胰岛素增敏剂等来控制疾病。而中医治疗NAFLD从病因病机出发,临床辨证中发现本病患者多呈脾虚症候,结合仲景之“见肝之病,知肝传脾,当先实脾”的理论,考虑脾失健运是NAFLD的关键病机,而健脾治肝为根本大法。本文将纵览从脾论治NAFLD相关临床和基础研究文献,从多角度论述中医药治疗本病的研究现状,为临床上运用健脾法治疗NAFLD提供理论依据,为深入中医药防治NAFLD的机制研究扩宽思路。The incidence of non-alcoholic fatty liver disease (NAFLD) increases year by year. In western medi-cine, liver-protecting drugs, lipid-lowering drugs and insulin sensitizers are usually used to control the disease. In the treatment of NAFLD in traditional Chinese medicine, the etiology and pathogene-sis were firstly investigated, and it was found in clinical syndrome differentiation that most patients with NAFLD presented the syndrome of spleen deficiency. In combination with Zhong Jing’s theory of “seeing the liver disease, knowing the liver and transmitting the spleen, and tonifying the spleen”, it was considered that the key pathogenesis of NAFLD was the spleen failing to be healthy and moving, and invigorating the spleen and treating the liver was the fundamental solution. This paper will review the related clinical and basic research articles on the treatment of NAFLD from the perspective of spleen, and discuss the research status of TCM treatment for NAFLD from multiple views, in order to provide a theoretical basis for the clinical treatment of NAFLD with the method of invigorating spleen, and broaden the thinking for further research on the mechanism of TCM prevention and treatment of NAFLD.

关 键 词：非酒精性脂肪性肝病 中医药 脾虚 

分 类 号：R57[医药卫生—消化系统]