髓鞘少突胶质细胞糖蛋白抗体相关视神经炎的研究进展  

Research Progress of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Optic Neuritis

作　　者：彭丘琳 李秀娟[1] 

机构地区：[1]重庆医科大学附属儿童医院神经内科,国家儿童健康与疾病临床医学研究中心,儿童发育疾病研究教育部重点实验室,儿科学重庆市重点实验室,重庆

出　　处：《临床医学进展》2023年第3期4853-4859,共7页Advances in Clinical Medicine

摘　　要：视神经炎(ON)是髓鞘少突胶质细胞糖蛋白抗体相关疾病(MOGAD)的常见临床表型,可导致急性或亚急性视力下降。MOG抗体相关视神经炎(MOG-ON)表现为严重视力损害,对类固醇依赖,且有较大的复发倾向,需要及早诊断及预防复发。了解MOG-ON的致病机制、临床特征、相关辅助检查、治疗及预后可为早期鉴别与提高诊治水平提供帮助。Optic neuritis (ON) is a common clinical phenotype of myelin oligodendrocyte glycoprotein anti-body-related disease (MOGAD) that can lead to acute or subacute vision loss. MOG antibody-asso- ciated optic neuritis (MOG-ON) presents with severe visual impairment, steroid dependence, and a greater tendency to relapse, which requires early diagnosis and prevention of recurrence. Under-standing the pathogenesis, clinical features, related auxiliary examinations, treatment and progno-sis of MOG-ON can help early identification and improve the level of diagnosis and treatment.

关 键 词：视神经炎(ON) 髓鞘少突胶质细胞糖蛋白抗体(MOG-Ab) 研究进展 

分 类 号：R73[医药卫生—肿瘤]