干细胞的外泌体在抗皮肤衰老中的研究进展  

Research Progress of Stem Cell Exosomes in Anti-Skin Aging

作　　者：宋元明 

机构地区：[1]内蒙古医科大学第一临床医学院,内蒙古 呼和浩特

出　　处：《临床医学进展》2023年第4期5153-5159,共7页Advances in Clinical Medicine

摘　　要：干细胞疗法主要是由于干细胞通过旁分泌途径发挥作用,而外泌体在旁分泌机制中起着关键作用。外泌体是细胞释放到细胞外的膜源性囊泡。干细胞来源的外泌体可以修复皮肤损伤,在再生医学中显示出巨大的治疗潜力。本综述主要讨论了间充质干细胞和诱导多能性干细胞来源的外泌体在抗皮肤衰老中的相关研究进展,并为使用干细胞来源的外泌体抗皮肤衰老提供了新的思路。Stem cell therapy is mainly due to stem cells acting through paracrine pathways, and exosomes play a key role in paracrine mechanisms. Exosomes are membrane-derived vesicles that are released by cells to the outside of the cell. Stem cell-derived exosomes can repair skin damage and show great potential in regenerative medicine. This review discusses the research progress of stem cell-derived exosomes in anti-skin aging, and provides new ideas for the use of stem cell-derived exosomes for anti-skin aging.

关 键 词：外泌体 细胞外囊泡 干细胞 皮肤衰老 间充质干细胞 诱导多能性干细胞 

分 类 号：R73[医药卫生—肿瘤]