儿童脓毒症与钙紊乱研究进展  

Research Progress on Sepsis and Disorder of Calcium in Children

作　　者：李凌霄 李静[1] 

机构地区：[1]重庆医科大学附属儿童医院重症医学科,国家儿童健康与疾病临床医学研究中心,儿童发育疾病研究教育部重点实验室,儿科学重庆市重点实验室,重庆

出　　处：《临床医学进展》2023年第4期6999-7005,共7页Advances in Clinical Medicine

摘　　要：近些年来,学者们发现儿童脓毒症与钙紊乱存在紧密联系,比如作为第二信使介导炎症发生、细胞凋亡、代谢改变,进而引起重要脏器的损伤等,在这一系列过程中钙紊乱从多种途径参与了脓毒症的发生发展。目前临床上对于儿童脓毒症低钙血症是否予以积极补钙尚无相关共识,本文试图通过对近些年国内外关于脓毒症与钙紊乱相关文献的查阅总结,进而对临床脓毒症相关钙紊乱处理提供参考。In recent years, scholars have found a strong association between childhood sepsis and calcium disorders. For example, as a second messenger mediates inflammation, apoptosis, metabolic changes, and consequently damage to vital organs. In this series of processes calcium disorders are involved in the development of sepsis in multiple ways. However, there is no clinical consensus on whether to actively supplement calcium in children with sepsis hypocalcemia. Therefore, this paper attempts to summarize the recent literature on sepsis and calcium disorders at home and abroad, and then provide a reference for the clinical management of sepsis-related calcium disorders.

关 键 词：儿童 脓毒症 钙离子 钙通道阻滞剂 钙增敏剂 

分 类 号：R73[医药卫生—肿瘤]