ADC值联合血清SCCA、CA125对宫颈癌患者的分期及病理的研究进展  

Research Progress of ADC Value Combined with Serum SCCA and CA125 in Staging and Pathology of Cervical Cancer Patients

作　　者：赵雅楠 尹桂秀[1] 

机构地区：[1]青海大学附属医院影像中心,青海 西宁

出　　处：《临床医学进展》2023年第7期10968-10973,共6页Advances in Clinical Medicine

摘　　要：宫颈癌被认为是一种危及生命的妇科疾病,在女性中排名第二。宫颈癌在全球妇女中的发病率和死亡率均处于领先地位。最新的研究表明,宫颈癌的发病率可能与人乳头瘤病毒(human papilloma-virus, HPV)感染、性激素失调、子宫颈炎症、不良的性行为以及过度的性行为有着千丝万缕的关联。当前,鳞状细胞癌已成为宫颈癌的主要类型,其发病率高达70%~80%,在宫颈癌患者中占据重要地位。非鳞状细胞癌占组织学中的少数,但其预后一般较差。血清鳞状上皮细胞癌抗原(squamous cell carcinoma antigen, SCCA)和血清糖类抗原(carbohydrate antigen, CA125)是临床公认的宫颈鳞癌筛查的首选标志物,有助于宫颈癌的诊断和早期发现。同时,我们也不可否认影像学检查对于诊断宫颈癌的一些帮助,例如,磁共振扩散加权成像(DWI)对改善宫颈癌的诊断、治疗反应预测和预后提供了有利价值。Cervical cancer is considered as a life-threatening gynecological disease, ranking second among women. Cervical cancer leads the world in morbidity and mortality among women. Recent research suggests that the incidence of cervical cancer may be inextricably linked to human papillomavirus (HPV) infection, sex hormone imbalance, cervical inflammation, poor sexual behavior and excessive sexual activity. At present, squamous cell carcinoma has become the main type of cervical cancer, its incidence is up to 70%~80%, occupying an important position in cervical cancer patients. Non-squamous cell carcinoma accounts for a minority of histology, but its prognosis is generally poor. Serum squamous cell carcinoma antigen (SCCA) and serum carbohydrate antigen (CA125) are widely recognized as the preferred markers for cervical squamous cell carcinoma screening, which contribute to the diagnosis and early detection of cervical cancer. At the same time, there is no denying the help of imaging examinations in the diagnosis of cervical cancer. For example, diffu-sion-weighted magnetic resonance imaging (DWI) has provided beneficial value in improving the diagnosis, treatment response prediction and prognosis of cervical cancer.

关 键 词：子宫颈癌 表观扩散系数 血清糖类抗原 血清鳞状上皮细胞癌抗原 

分 类 号：R73[医药卫生—肿瘤]