NLR联合彩色多普勒超声显像评分评估结石性胆囊炎的严重程度及临床价值  

NLR Combined with Color Doppler Ultrasonography Score to Evaluate the Severity and Clinical Value of Calculous Cholecystitis

作　　者：黄文胤 费书珂 欧阳征仁 杨琴 谢学文 

机构地区：[1]南华大学附属第二医院超声科,湖南 衡阳

出　　处：《临床医学进展》2023年第8期13766-13771,共6页Advances in Clinical Medicine

摘　　要：目的:研究中性粒细胞与淋巴细胞比值(NLR)联合彩色多普勒超声显像评分评估结石性胆囊炎的严重程度及临床价值。方法:选择我院2021年1月~2022年4月收治的100例结石性胆囊炎患者作为观察组。另选取同期单纯胆囊结石患者500例作为对照组。检测并比较两组NLR、降钙素原(PCT)以及C反应蛋白(CRP)水平。观察组结石性胆囊炎按临床表现分为轻、中、重度,所有患者均进行彩色多普勒超声检查,分析不同病情严重程度结石性胆囊炎患者的超声显像评分以及血清NLR、PCT、CRP水平的差异。结果:观察组血清NLR、PCT以及CRP水平分别为(8.17 ± 1.04)、(2.66 ± 0.44) ng/ml、(52.34 ± 12.35) mg/L,均高于对照组的(5.11 ± 0.95)、(1.92 ± 0.35) ng/ml、(20.47 ± 7.12) mg/L (均P < 0.05)。中度组、重度组彩色多普勒超声显像评分 ≤ 5分人数占比均低于轻度组,而≥10分人数占比均高于轻度组,且重度组≥10分人数占比高于中度组;中度组彩色多普勒超声显像评分6~9分人数占比均高于轻度组、重度组(均P < 0.05)。重度组血清NLR、PCT以及CRP水平分别为(13.34 ± 1.45)、(4.35 ± 0.59) ng/ml、(77.58 ± 16.22) mg/L,均高于轻度组的(6.42 ± 0.39)、(1.48 ± 0.46) ng/ml、(42.49 ± 6.29) mg/L以及中度组的(8.05 ± 1.12)、(2.63 ± 0.47) ng/ml、(50.89 ± 10.36) mg/L;且中度组血清NLR、PCT以及CRP水平均高于轻度组(均P < 0.05)。结论:NLR联合彩色多普勒超声显像评分评估结石性胆囊炎的严重程度具有较高临床价值。Objective: To study the severity and clinical value of neutrophil to lymphocyte ratio (NLR) combined with color Doppler ultrasonography score in evaluating calculous cholecystitis. Methods: 100 pa-tients with calculous cholecystitis treated in our hospital from January 2021 to April 2022 were se-lected as the observation group. Another 500 patients with simple gallstone in the same period were selected as the control group. The levels of NLR, procalcitonin (PCT) and C-reactive protein (CRP) were detected and compared between the two groups. The observation group was divided into mild, moderate and severe calculous cholecystitis according to clinical manifestations, color Doppler ultrasonography was performed on all observation groups, and the differences of ultrasonic imaging score and serum NLR, PCT and CRP levels in patients with different severity of calculous cholecystitis were analyzed. Results: Serum NLR, PCT and CRP levels in observation group were (8.17 ± 1.04), (2.66 ± 0.44) ng/mL and (52.34 ± 12.35) mg/L, respectively, which was higher than control group (5.11 ± 0.95), (1.92 ± 0.35) ng/mL, (20.47 ± 7.12) mg/L (P < 0.05). The proportion of patients with color Doppler imaging score ≤ 5 in moderate group and severe group was lower than that in mild group, while the proportion of patients with color Doppler imaging score ≥ 10 was higher than that in mild group, and the proportion of patients with color Doppler imaging score ≥ 10 in severe group was higher than that in moderate group. The proportion of color Doppler ultra-sonography score of 6~9 in moderate group was higher than that in mild group and severe group (P < 0.05). Serum NLR, PCT and CRP levels in severe group were (13.34 ± 1.45), (4.35 ± 0.59) ng/ mL and (77.58 ± 16.22) mg/L, respectively, higher than those in mild group (6.42 ± 0.39), (1.48 ± 0.46) ng/ml, (42.49 ± 6.29) mg/L and moderate group (8.05 ± 1.12), (2.63 ± 0.47) ng/ml, (50.89 ± 10.36) mg/L. Serum NLR, PCT and CRP levels in moderate group were higher than those in m

关 键 词：结石性胆囊炎 彩色多普勒超声 中性粒细胞与淋巴细胞比值 降钙素原 C反应蛋白 

分 类 号：R73[医药卫生—肿瘤]