颈动脉粥样硬化易损斑块与血液生物标记物研究进展  

Research Progress of Carotid Atherosclerotic Plaques and Blood Biomarkers

作　　者：刘毅恒 侯倩[2] 

机构地区：[1]青海大学研究生院,青海 西宁 [2]青海省人民医院神经内科,青海 西宁

出　　处：《临床医学进展》2023年第10期16870-16875,共6页Advances in Clinical Medicine

摘　　要：动脉粥样硬化是缺血性脑卒中的重要病理基础,其中30%由颈动脉粥样硬化性疾病引起。颈动脉易损斑块破裂、溃疡、血小板活化、血栓形成引起的动脉血栓被认为是缺血性脑卒中的发病机制,所以早期发现和治疗颈动脉易损斑块对缺血性脑卒中有着重大意义,研究表明,除了分子影像技术外,血液生物标记物也可为颈动脉斑块稳定性提供一定的诊断价值。Atherosclerosis is an important pathological basis of ischemic stroke, 30% of which are caused by carotid atherosclerotic diseases. Arterial thrombosis caused by rupture, ulceration, platelet activa-tion and thrombosis of vulnerable carotid plaque are considered to be the pathogenesis of ischemic stroke. Therefore, early detection and treatment of vulnerable carotid plaque are of great signifi-cance for ischemic stroke. Studies have shown that in addition to molecular imaging technology, blood biomarkers can also provide certain diagnostic value for the stability of carotid plaque.

关 键 词：缺血性脑卒中 颈动脉粥样硬化 易损斑块 生物标记物 

分 类 号：R74[医药卫生—神经病学与精神病学]