乳腺癌中糖代谢研究进展  

Research Progress of Glucose Metabolism in Breast Cancer

作　　者：董林桓 张先林[1] 

机构地区：[1]三峡大学附属仁和医院,湖北 宜昌

出　　处：《临床医学进展》2023年第12期18610-18616,共7页Advances in Clinical Medicine

摘　　要：乳腺癌仍是女性死亡的主要原因。常规的化疗方式与靶向治疗及免疫治疗的结合能够改善患者的预后,提高患者的生存率。尽管临床试验中都报告出了令人鼓舞的结果,但是仍有许多未解决的一些障碍。这篇综述,将跳过糖代谢作为能量存储方式的一种传统理解,转而去描述糖代谢在肿瘤的生成中所起到的作用,为乳腺癌的发病机制及潜在治疗方式提供新思路。Breast cancer remains the leading cause of death among women. Combining conventional chemo-therapy with targeted therapy and immunotherapy can improve patient prognosis and increase survival rates. Despite encouraging results reported in clinical trials, there are still many unre-solved obstacles. This review aims to move beyond the traditional understanding of sugar metabo-lism as an energy storage mechanism and instead describe its role in tumor formation, providing new insights into the pathogenesis of breast cancer and potential treatment approaches.

关 键 词：乳腺癌 糖原合成 糖原合成激酶 

分 类 号：R73[医药卫生—肿瘤]