实验室检查指标对发热伴血小板减少综合征的早期诊断及预后的影响分析  

Analysis of Laboratory Indicators on Early Diagnosis and Prognosis of Fever with Thrombocytopenia Syndrome

作　　者：潘磊 段建平 

机构地区：[1]青岛大学医学院,山东 青岛 [2]莒南县人民医院呼吸与危重医学科,山东 临沂 [3]青岛第六人民医院感染科,山东 青岛

出　　处：《临床医学进展》2023年第12期18796-18800,共5页Advances in Clinical Medicine

摘　　要：目的:浅析发热伴血小板减少综合征开展实验室检查对疾病早期诊断和预后分析的价值,为后续的临床检查以及治疗分析提供数据参考。方法:回顾分析2023年5月至2023年10月期间在我院接受治疗的43例发热伴血小板减少综合征患者,并根据其治疗情况分为死亡组(12例)及生存组(31例),分析两组患者入院24 h之内的白细胞、血小板、血钙等实验室指标,并开展多因素Logistic回归分析,找到相关因素。结果:死亡组患者的病毒载量、血钙等指标均高于生存组(P < 0.05);多因素分析发现高病毒栽量、高炎症反应、肾功能障碍等是引起患者死亡的独立危险因素。结论:发热伴血小板减少综合征患者早期存在血钙以及病毒载量高等特点,后续诊疗中可以根据实验室指标判断患者的情况。Objective: To analyze the value of febrile thrombocytopenia syndrome for early diagnosis and prognosis analysis, and to provide data reference for subsequent clinical examination and treat-ment analysis. Methods: Reviewed and analyzed 43 patients with fever and thrombocytopenia syn-drome treated in our hospital from May 2023 to October 2023, and divided into death group (12 cases) and survival group (31 cases) according to their treatment situation, analyzed the laboratory indicators such as white blood cells, platelets and blood calcium within 24 h of admission, and car-ried out multivariate Logistic regression analysis to find the relevant factors. Results: The viral load and blood calcium were higher than the survival group (P < 0.05);high viral dose, high inflamma-tion, and renal dysfunction were independent risk factors. Conclusion: Patients with fever with thrombocytopenia syndrome are characterized by blood calcium and high viral load in the early stage, which can be judged according to laboratory indicators in subsequent diagnosis and treat-ment.

关 键 词：发热伴血小板减少综合征 实验室分析 新型布尼亚病毒 

分 类 号：R73[医药卫生—肿瘤]