抗抑郁药预防治疗慢性偏头痛的研究进展  

Advances in Antidepressant Prophylaxis for the Treatment of Chronic Migraine Headache

作　　者：余震[1] 秦华兰 李倩[1] 蒋兆雪 

机构地区：[1]重庆医科大学附属第二医院神经内科,重庆

出　　处：《临床医学进展》2024年第1期2028-2035,共8页Advances in Clinical Medicine

摘　　要：慢性偏头痛是一种神经系统疾病,易与焦虑抑郁等共病,造成严重经济负担,需积极开展预防及治疗。本文概述了近5年来抗抑郁药物预防治疗慢性偏头痛的现状,总结了这些药物的有效性和安全性。认为文拉法辛优于阿米替林,A型肉毒毒素可以作为潜在的预防治疗慢性偏头痛药物。Chronic migraine is a neurological disorder that is prone to co-morbidities such as anxiety and de-pression, resulting in a serious economic burden that requires active prevention and treatment. This article outlines the current status of antidepressant medications for the prophylactic treat-ment of chronic migraine over the past 5 years and summarizes the effectiveness and safety of these medications. It is concluded that venlafaxine is superior to amitriptyline and that botulinum toxin type A can be used as a potential prophylactic treatment for chronic migraine.

关 键 词：慢性偏头痛 抗抑郁药 A型肉毒毒素 

分 类 号：R74[医药卫生—神经病学与精神病学]