心脏右心房未分化肉瘤1例并文献回顾  

Undifferentiated Sarcoma of the Right Atrium: A Case Report and Literature Review

作　　者：杨新萌 邱水玮 邢泉生[1] 

机构地区：[1]青岛大学附属妇女儿童医院,山东 青岛 [2]温州医科大学附属衢州医院,浙江 衢州

出　　处：《临床医学进展》2024年第2期2939-2945,共7页Advances in Clinical Medicine

摘　　要：目的:探讨原发性心脏未分化肉瘤的临床症状、影像学检查及病理表现特点。方法:对温州医科大学附属衢州医院收治的1例心脏未分化肉瘤患者的临床资料进行回顾性分析,并以“心脏未分化肉瘤”为关键词,检索中国知网、万方数据库和中华医学期刊全文数据库,以“cardiac undifferentiated sarcoma”为关键词检索PubMed数据库,检索时间自建库至2023年12月,总结原发性心脏未分化肉瘤的临床症状、影像学检查及病理表现特点。结果:检索国内外文献共收集到原发性心脏未分化肉瘤47例,加上本例共48例。原发性心脏未分化肉瘤患者临床表现为进行性呼吸困难、双下肢水肿、乏力、咳嗽咳痰、胸痛。发病部位位于右心房5例,右心室9例,左心房19例,左心室8例,心包2例,未明确3例。最小年龄为1岁,最大发病年龄为87岁,其中50~70岁发病23例。结论:心脏未分化肉瘤患者的临床表现多样,不具有典型性,以进行性呼吸困难最多见;超声心动图对于诊断具有重要意义,最终确诊仍需病理检查。Objective: To investigate the clinical symptoms, imaging and pathological features of primary car-diac undifferentiated sarcoma. Methods: The clinical data of one patient with cardiac undifferenti-ated sarcoma admitted to Quzhou Hospital Affiliated to Wenzhou Medical University were retro-spectively analyzed. “Cardiac undifferentiated sarcoma” was used as the key word to search China National Knowledge Infrastructure (CNKI), Wanfang Database and Chinese Medical Journal Full-text Database. “Cardiac undifferentiated sarcoma” was used as the key word to search PubMed database. The search time was from the establishment of the database to December 2023. The clinical symp-toms, imaging examination and pathological features of primary cardiac undifferentiated sarcoma were summarized. Results: A total of 47 cases of primary cardiac undifferentiated sarcoma were collected from domestic and foreign literatures;including this example, there are a total of 48 cases. The clinical manifestations of patients with primary cardiac undifferentiated sarcoma were pro-gressive dyspnea, edema of both lower limbs, fatigue, cough and expectoration, and chest pain. The location of the disease was located in the right atrium in 5 cases, right ventricle in 9 cases, left atrium in 19 cases, left ventricle in 8 cases, pericardium in 2 cases, and unclear in 3 cases. The minimum age was 1 year old, and the maximum age of onset was 87 years old, including 23 cases of 50~70 years old. Conclusions: The clinical manifestations of patients with cardiac undifferentiated sarcoma are diverse and not typical. Progressive dyspnea was the most common symptom;echo-cardiography is of great significance for diagnosis, and final diagnosis still requires pathological examination.

关 键 词：心脏 未分化肉瘤 诊断 影像检查 临床病理 

分 类 号：R73[医药卫生—肿瘤]