中医中药治疗结直肠癌的研究进展  

Research Progress of Traditional Chinese Medicine in the Treatment of Colorectal Cancer

作　　者：雷雪 张俐佳 尹新宇 李晓琴 刘松江[2] 

机构地区：[1]黑龙江中医药大学研究生院,黑龙江 哈尔滨 [2]黑龙江中医药大学附属第一医院,黑龙江 哈尔滨

出　　处：《临床医学进展》2024年第3期1360-1368,共9页Advances in Clinical Medicine

摘　　要：结直肠癌(Colorectal Cancer, CRC)是一种临床常见的消化道恶性肿瘤。近年来CRC的发病率和死亡率逐年增加,对于CRC的临床治疗也趋于多样化。西医治疗主要以手术、化疗、放疗、靶向治疗等为主,然而西医治疗后的并发症及治疗中的不良反应严重影响患者的生存质量。越来越多的研究表明中医中药对放疗、化疗可以起到减毒增效的作用,中药主要通过诱导肿瘤细胞凋亡、抑制细胞增殖与肿瘤血管生成、调控信号传导通路和肿瘤微环境等方式作用于CRC。本文就中医中药治疗CRC的机制及临床研究概况作综合阐述,为未来的深入研究提供参考。Colorectal cancer (CRC) is a clinically common malignant tumor of the digestive tract. The morbidity and mortality of CRC have increased year by year in recent years, and the clinical treatment of CRC also tends to diversify. Western medical treatment is mainly based on surgery, chemotherapy, radiotherapy, targeted therapy, etc., however, complications after Western medical treatment and adverse reactions in treatment seriously affect the quality of patient survival. An increasing number of studies have shown that TCM can exert an attenuated and synergistic effect on radiotherapy and chemotherapy, and TCM mainly acts on CRC by inducing tumor cell apoptosis, inhibiting cell proliferation and tumor angiogenesis, regulating signaling pathways and the tumor microenvironment. This article provides a comprehensive illustration of the mechanism and clinical research profile of traditional Chinese medicine (TCM) for the treatment of CRC, and provides a reference for future in-depth studies.

关 键 词：中医中药 肿瘤 结直肠癌 综述 

分 类 号：R73[医药卫生—肿瘤]