腺泡状软组织肉瘤37例临床病理学分析  

Clinical Pathological Analysis of 37 Cases of Alveolar Soft Part Sarcoma

作　　者：张珍琦 陈召旭 李丹[2] 王瑞清 邢晓明[2] 

机构地区：[1]青岛大学医学部,山东 青岛 [2]青岛大学附属医院病理科,山东 青岛

出　　处：《临床医学进展》2024年第3期1550-1557,共8页Advances in Clinical Medicine

摘　　要：目的:讨论腺泡状软组织肉瘤的临床病理特征、影像学特点、治疗方式及预后情况。方法:收集2007年11月至2021年8月于青岛大学附属医院就诊,并经病理证实为腺泡状软组织肉瘤的37例患者的临床资料,对其临床病理特征、组织形态学特点、影像学特征、免疫表型及预后情况进行回顾性分析。结果:37例患者中男性17例(46%),女性20例(54%),中位年龄为24岁。发病部位大多位于下肢(16例,43%),常早期伴随远处转移(18例,48.7%),五年生存率64.4%。结论:ASPS起病隐匿,发病年龄较轻,早期诊断并行扩大切除手术是良好预后的重要因素,较为特征性的影像学及组织病理学表现对于疾病的明确诊断具有重要的价值。Objective: To discuss the clinical and pathological characteristics, imaging features, treatment modalities, and prognosis of Alveolar Soft Part Sarcoma (ASPS). Methods: Clinical data were collected from 37 patients diagnosed with ASPS between November 2007 and August 2021 at the Affiliated Hospital of Qingdao University. Retrospective analysis was conducted to assess clinical and pathological features, histological characteristics, imaging findings, immunophenotype, and prognosis. Results: Among the 37 patients, 17 (46%) were male, and 20 (54%) were female, with a median age of 24 years. The majority of cases involved the lower limbs (16 cases, 43%), often presenting with distant metastasis at an early stage (18 cases, 48.7%). The five-year survival rate was 64.4%. Conclusion: ASPS is characterized by insidious onset, occurring at a young age, and early diagnosis with extensive surgical resection is a crucial factor for a favorable prognosis. Distinctive imaging and histopathological features play a significant role in the accurate diagnosis of the disease.

关 键 词：腺泡状软组织肉瘤 影像 病理 预后 

分 类 号：R73[医药卫生—肿瘤]