¹⁸F-FDG PET/CT在神经母细胞瘤诊疗过程中的价值评估  

Evaluation of the Value of 18F-FDG PET/CT in the Diagnosis and Treatment of Neuroblastoma

作　　者：甘恩 李时望[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院小儿外科,湖北 武汉

出　　处：《临床医学进展》2024年第4期1395-1401,共7页Advances in Clinical Medicine

摘　　要：神经母细胞瘤(Neuroblastoma, NB)是婴幼儿最常见的颅外实体肿瘤,各患儿的临床表现、疗效及预后等方面存在较大差异,肿瘤可自然消退或广泛转移,约有半数患儿就诊时即存在多处转移,分期较晚。18F氟代脱氧葡萄糖正电子发射断层扫描(18F-FDG PET/CT)已经广泛应用于成人肿瘤的诊疗过程中,但在儿童实体肿瘤中的应用相对滞后。本文对近十年来NB的研究进行了文献综述,阐述了18F-FDG PET/CT在NB患儿从诊断、分期、预后、治疗到复发监测整个诊疗过程中的指导意义。Neuroblastoma (NB) is the most common extracranial solid tumor in young children, and there are great differences in the clinical manifestations, efficacy and prognosis of each child. Tumors may resolve spontaneously or metastasize extensively, and about half of children present with multiple metastases and late stage. 18F fluorodeoxyglucose positron emission tomography (18F-FDG PET/CT) has been widely used in the diagnosis and treatment of adult tumors, but its application in pediatric solid tumors is relatively lagging behind. This article reviews the literature on NB in the past decade, and expounds the guiding significance of 18F-FDG PET/CT in the whole diagnosis and treatment of children with NB from diagnosis, staging, prognosis, to recurrence monitoring.

关 键 词：神经母细胞瘤 ¹⁸F-FDG PET/CT 小儿实体瘤 诊断 分期 预后 复发监测 

分 类 号：R73[医药卫生—肿瘤]