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机构地区:[1]延安大学附属医院肿瘤科,陕西 延安
出 处:《临床医学进展》2024年第7期365-371,共7页Advances in Clinical Medicine
摘 要:代谢综合征是一种常见的代谢性疾病,包括肥胖、高血压、高血糖和高胆固醇。与绝经后乳腺癌患者之间存在一定的关联。越来越多的证据表明代谢综合征与绝经后乳腺癌风险增加之间存在关联。其影响机制可能涉及胰岛素、胰岛素样生长因子-1、高胰岛素血症、雌激素、脂肪因子、炎症因子等多种因子。本文就代谢综合征与绝经后乳腺癌患者的相关性研究进展做一概述,为绝经后乳腺癌的预防、治疗提供新思路。Metabolic syndrome is a common metabolic disorder that includes obesity, high blood pressure, high blood sugar, and high cholesterol. There is an association with postmenopausal breast cancer patients. There is growing evidence of an association between metabolic syndrome and an increased risk of breast cancer after menopause. The influencing mechanism may involve a variety of factors such as insulin, insulin-like growth factor-1, hyperinsulinemia, estrogen, adiptenoid, and inflammatory factors. This article summarizes the research progress on the correlation between metabolic syndrome and postmenopausal breast cancer, and provides new ideas for the prevention and treatment of postmenopausal breast cancer.
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