复合恩施玉露茶预防脂代谢紊乱的作用研究  

Preventive Effect of Compound Enshi Yulu Tea on Lipid Metabolism Disorder

作　　者：刘慎思 刘本德 

机构地区：[1]华中科技大学同济医学院附属协和医院,湖北 武汉

出　　处：《临床医学进展》2024年第11期1143-1150,共8页Advances in Clinical Medicine

摘　　要：目的:探究复合恩施玉露茶在调节脂代谢过程中的作用。方法:将40只小鼠随机分为4组:健康对照组、高脂对照组、复合茶组、阿托伐他汀组。以高脂饲料喂养建立高脂血症模型后,分别给予生理盐水、生理盐水、复合恩施玉露茶、阿托伐他汀每日1次灌胃。4周后收集小鼠标本检测。结果:结果表明,复合茶水溶液可以显著降低小鼠血清胆固醇、甘油三酯、低密度脂蛋白的水平,提高高密度脂蛋白含量。提高肝脂肪酶(HL)、激素敏感性脂肪酶(HSL)水平,并降低炎症因子TNF-α、IL-6及IFN-γ的水平。结论:复合茶可能通过提高肝脂肪酶和激素敏感性脂肪酶水平调节小鼠脂质代谢,并且具有抗炎作用。Objective: To explore the role of compound Enshi Yulu tea in regulating lipid metabolism. Method: 40 mice were randomly divided into 4 groups: healthy control group, hyperlipidemia control group, compound tea group, and atorvastatin group. After the hyperlipidemia model was established by feeding with the high-fat diet, normal saline, normal saline, composite tea and atorvastatin were administered by gavage once a day. Mice specimens were collected for detection after 4 weeks. Outcome: The results showed that the composite tea soup could significantly reduce the levels of serum cholesterol, triglyceride and low-density lipoprotein, and increase the content of high-density lipoprotein in mice. After the composite tea intervention, the hepatic lipase gene and hormone-sensitive lipase gene level of mice increased, meanwhile, the levels of inflammation factors, such as TNF-α, IL-6 and IFN-γ were reduced. Conclusion: Compound tea may regulate lipid metabolism in mice by increasing hepatic lipase and hormone-sensitive lipase levels and has anti-inflammatory effects.

关 键 词：恩施玉露茶 肝脂肪酶 激素敏感性脂肪酶 高脂血症 

分 类 号：R73[医药卫生—肿瘤]