基于分化程度直肠癌DCE-MRI定量参数及其相关临床危险因素的进展  

Progress of Quantitative Parameters of Rectal Cancer DCE-MRI and Its Related Clinical Risk Factors Based on Differentiation Degree

作　　者：向美玲 邬颖华 

机构地区：[1]成都中医药大学医学与生命科学学院,四川 成都 [2]成都中医药大学附属医院放射影像科,四川 成都

出　　处：《临床医学进展》2024年第11期233-241,共9页Advances in Clinical Medicine

摘　　要：据全球直肠癌流行病学调查显示,直肠癌发病率位列第八,是一种常见的恶性肿瘤。对于直肠癌早期的病灶影像学特征及相关临床危险因素的分析有助于直肠癌的早预防、早诊断、早治疗。磁共振成像因其结构和功能成像的双重价值,在直肠癌的早期诊断、分化分级和淋巴结转移情况等具有明显的优势。其中尤其以磁共振动态对比增强扫描(Magnetic resonance dynamic enhanced scan, DCE-MRI)及磁共振弥散加权成像(Magnetic resonance imaging diffusion weighted imaging, DWI-MRI)在评估直肠癌的病理分化程度方面具有相对较高的价值。基于此,本文就不同分化程度直肠癌的DCE-MRI、DWI-MRI定量参数值变化以及直肠癌患者的病理分化程度与患者营养代谢紊乱的关联进展进行综述,以期为今后的相关方面研究提供参考。According to the latest global epidemiological survey of rectal cancer, rectal cancer incidence ranks eighth and is a common malignancy. The analysis of the imaging characteristics of the lesions and related clinical risk factors of rectal cancer is conducive to the early prevention, early diagnosis and early treatment of rectal cancer. Because of its dual value of structural and functional imaging, MR imaging has obvious advantages in the early diagnosis of rectal cancer, differentiation grade, and lymph node metastasis. In particular, the magnetic resonance dynamic enhanced scan (DCE-MRI) and Magnetic resonance imaging diffusion weighted imaging (DWI-MRI) have a relatively high value in evaluating the degree of pathological differentiation of rectal cancer. Based on this, we will review the changes of DCE-MRI and DWI-MRI quantitative parameters in rectal cancer with different degrees of differentiation, as well as the correlation between the degree of pathological differentiation and nutritional and metabolic disorders in patients with rectal cancer.

关 键 词：直肠癌 磁共振动态对比增强扫描 磁共振弥散加权成像 营养代谢紊乱 

分 类 号：R73[医药卫生—肿瘤]