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作 者:潘振宇
出 处:《临床医学进展》2024年第12期1524-1529,共6页Advances in Clinical Medicine
摘 要:门静脉动脉化(portal vein arterialization, PVA)自首次被提出之后,经过不断的发展和完善已成功应用于肝移植、腹部恶性肿瘤和急性肝衰竭等领域。肝脏是一种再生能力很强的器官,其能否在一定程度上恢复到正常的大小和功能直接影响到手术的成败。PVA在肝再生方面的作用一直是一个热门话题。然而,其对肝脏再生的影响及机制还没有完全明确。为此,本文综述PVA对肝再生的作用及影响机制,并对PVA今后的研究方向及应用前景进行展望。Since it was first proposed, portal vein arterialization (PVA) has been successfully applied to liver transplantation, abdominal malignancies and acute liver failure after continuous development and improvement. The liver is an organ with strong regenerative ability, and whether it can recover to a certain extent to normal size and function directly affects the success or failure of the operation. The role of PVA in liver regeneration has been a hot topic. However, its effect on liver regeneration and its mechanism have not been fully clarified. In this paper, the effects and mechanisms of PVA on liver regeneration were reviewed, and the future research direction and application prospect of PVA were also discussed.
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