维生素D3辅助治疗变应性鼻炎的疗效及对外周血嗜酸性粒细胞的影响  

Effect of Vitamin D3 in Adjuvant Treatment of Allergic Rhinitis and Its Influence on Peripheral Blood Eosinophils

作　　者：艾合买提江·艾力江 郭小平[1] 

机构地区：[1]新疆维吾尔自治区人民医院耳鼻喉诊疗中心,新疆 乌鲁木齐

出　　处：《临床医学进展》2025年第1期670-675,共6页Advances in Clinical Medicine

摘　　要：目的:探讨维生素D3辅助治疗变应性鼻炎(AR)的疗效及对外周血嗜酸性粒细胞(EOS)的影响。方法:选取该院2023年7月~2024年6月的82例AR患者,随机分为A组与B组。A组41例给予枸地氯雷他定治疗,B组41例在A组基础上给予维生素D3治疗,比较2组患者的临床疗效、症状缓解时间、血清相关指标。结果:B组的临床疗效总有效率为95.12%,高于A组的80.49%,P P P Objective: To investigate the therapeutic effect of vitamin D3 adjuvant therapy on allergic rhinitis (AR) and its impact on peripheral blood eosinophils (EOS). Method: 82 AR patients from July 2023 to June 2024 in the hospital were randomly divided into Group A and Group B. 41 patients in Group A were treated with desloratadine citrate, while 41 patients in Group B were treated with vitamin D3 in addition to Group A. The clinical efficacy, symptom relief time, and serum related indicators of the two groups were compared. Result: The total effective rate of clinical efficacy in Group B was 95.12%, higher than Group A’s 80.49%, P P P < 0.001. Conclusion: Vitamin D3 adjuvant therapy has a good therapeutic effect on AR, which can accelerate symptom relief, reduce EOS infiltration and ECP release, and lower IgE levels. It is worth promoting.

关 键 词：维生素D3 枸地氯雷他定 临床疗效 外周血嗜酸性粒细胞 

分 类 号：R73[医药卫生—肿瘤]