牙本质基质材料在牙和骨组织再生中的应用  

Applications of Dentin Matrix Materials in Tooth and Bone Tissue Regeneration

作　　者：胡珊 杨明聪 

机构地区：[1]重庆医科大学口腔医学院,重庆

出　　处：《临床医学进展》2025年第2期1102-1110,共9页Advances in Clinical Medicine

摘　　要：损伤组织的修复与再生一直是生物学和医学领域的重要研究课题。牙齿和骨组织缺损是临床中常见的疾病问题。与软组织不同,牙齿和骨等硬组织的再生修复具有其独特的特点。支架在组织工程中起着至关重要的作用,为组织修复与再生提供必要的微环境。牙本质基质是一种无细胞的天然生物活性支架,具有优异的生物相容性,已广泛应用于硬组织的再生修复。本文综述了牙本质基质的生物学特性、材料种类及其在组织再生中的应用,为未来牙本质基质材料的基础研究与临床应用提供参考。The repair and regeneration of damaged tissues have long been a key focus of research in biology and medicine. Tooth and bone tissue defects are common clinical issues. Unlike soft tissues, the regeneration and repair of hard tissues, such as teeth and bones, involve distinct processes. Scaffolds play a crucial role in tissue engineering by providing the necessary microenvironment for tissue repair and regeneration. The dentin matrix is a cell-free, natural bioactive scaffold with excellent biocompatibility, widely used in the regeneration and repair of hard tissues. This article reviews the biological properties of the dentin matrix, its material types, and applications in tissue regeneration, offering a reference for future basic research and clinical applications of dentin matrix materials.

关 键 词：牙本质基质 牙本质再生 骨再生 牙周再生 

分 类 号：R78[医药卫生—口腔医学]