智能手机比色分析在生物标志物检测中的应用  

Application of Smartphone-Based Colorimetric Analysis in Biomarker Detection

作　　者：白刚 余华 

机构地区：[1]成都中医药大学医学与生命科学学院,四川 成都 [2]成都中医药大学附属医院普外科,四川 成都

出　　处：《临床医学进展》2025年第2期1942-1951,共10页Advances in Clinical Medicine

基　　金：四川省科技计划(MZGC20240006);成都中医药大学“杏林学者”课题研究自由探索专项(ZYTS2024007)。

摘　　要：智能手机比色分析是一种新兴的检测技术,结合了智能手机的便携性与比色分析的高灵敏度和低成本优势,在生物标志物检测中展现出重要应用价值。生物标志物广泛用于疾病的诊断、治疗效果评估及预后监测。近年来,研究表明,智能手机辅助比色分析技术能够实现多种生物标志物的快速、精准检测,尤其在资源有限地区和即时检测中具有独特优势。本文系统综述了智能手机比色分析技术在各种生物标志物检测中的最新研究进展,并探讨了其在医学诊断中的未来发展方向以及可能面临的挑战与解决策略。Smartphone-based colorimetric analysis is an emerging detection technology that combines the portability of smartphones with the high sensitivity and low-cost advantages of colorimetric analysis, demonstrating significant application value in biomarker detection. Biomarkers are widely used in disease diagnosis, therapeutic efficacy evaluation, and prognostic monitoring. Recent studies have shown that smartphone-assisted colorimetric analysis enables rapid and accurate detection of various biomarkers, offering unique advantages particularly in resource-limited settings and point-of-care testing. This paper systematically reviews the latest research progress of smartphone-based colorimetric analysis technology in the detection of various biomarkers, explores its future development directions in medical diagnostics, and discusses potential challenges and corresponding solutions.

关 键 词：智能手机 比色分析 生物标志物 检测 

分 类 号：R73[医药卫生—肿瘤]