孟德尔随机化方法在子宫内膜癌研究中的应用现状与展望  

The Application Status and Prospects of the Mendelian Randomization Method in Endometrial Cancer Research

作　　者：沙怡 孙晓青 谭宏伟 

机构地区：[1]西安医学院研究生工作部,陕西 西安 [2]西北妇女儿童医院妇科,陕西 西安

出　　处：《临床医学进展》2025年第3期2004-2009,共6页Advances in Clinical Medicine

摘　　要：孟德尔随机化(Mendelian Randomization, MR)作为一种基于遗传变异的因果推断方法,近年来在子宫内膜癌的风险因素研究中获得广泛应用。文章综述了孟德尔随机化方法在子宫内膜癌风险因素中的应用进展,以期为子宫内膜癌因果关系的研究提供新思路。Mendelian Randomization (MR), as a genetic variant-based causal inference method, has been widely applied in recent years to the study of risk factors for endometrial cancer. This article reviews the progress in the application of the Mendelian Randomization method to the investigation of risk factors for endometrial cancer, aiming to provide new insights for research into causal relationships in endometrial cancer.

关 键 词：子宫内膜癌 孟德尔随机化分析 危险因素 相关性 

分 类 号：R737.33[医药卫生—肿瘤]