经颅直流电刺激延缓情景记忆老化的微观机制  

Mechanism of Transcranial Direct Current Stimulation Reducing Episodic Memory Aging

作　　者：李朝会 

机构地区：[1]西南大学心理学部,重庆

出　　处：《社会科学前沿》2023年第4期1778-1785,共8页Advances in Social Sciences

摘　　要：情景记忆是受老化影响最严重的长期记忆。经颅直流电刺激可以延缓情景记忆老化,并且有研究对其干预机制做出初步探讨,但尚未有研究进行系统梳理。本文基于情景记忆老化的神经生物学基础研究,从微观层面对经颅直流电刺激的干预机制进行探讨。在微观(分子、细胞)水平,经颅直流电刺激通过诱导膜电位变化、调节神经递质系统以及脑源性神经营养因子来影响突触可塑性,从而延缓情景记忆的老化。Episodic memory is the long-term memory most affected by aging. Transcranial direct current stimulation can delay episodic memory aging, and its intervention mechanism has been prelimi-narily discussed. Based on the basic neurobiological research of episodic memory aging, this pa-per discusses the intervention mechanism of transcranial direct current stimulation from the micro level. At the microscopic (molecular, cellular) level, transcranial direct current stimulation affects synaptic plasticity by inducing changes in membrane potential, modulating neurotransmitter systems, and brain-derived neurotrophic factors, thereby delaying episodic memory aging.

关 键 词：情景记忆 经颅直流电刺激 老化 干预 神经递质 

分 类 号：R74[医药卫生—神经病学与精神病学]