检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
作 者:张云波[1] 郑丽萍[2] 李沐阳 张林 李锦秋 吕静[5] 郑欢欢 张建光[1]
机构地区:[1]淄博万杰肿瘤医院肿瘤科,山东 淄博 [2]淄博万杰肿瘤医院病案室,山东 淄博 [3]昌邑市人民医院肾内科,山东 昌邑 [4]天津二七二医院放射科,天津 [5]淄博万杰肿瘤医院病理科,山东 淄博
出 处:《临床个性化医学》2025年第1期273-278,共6页Journal of Clinical Personalized Medicine
基 金:淄博市医药卫生科研项目(20230903085);山东省医药卫生科技项目(202409030400)。
摘 要:目的:探讨放疗体积和不同放疗技术在胸部肿瘤中对淋巴细胞(Lymphocyte, Lym)及其亚群分布影响。方法:选取我科胸部恶性肿瘤放疗患者,通过测量靶区体积,计算放疗前后淋巴细胞的差值(ΔLym),进行相关性分析。对光子放疗组和质子放疗组治疗后Lym及其亚群分布进行比较。结果:ΔLym与靶区体积通过散点图观察无明显相关性。Pearson相关性分析r = 0.079,P = 0.672。在质子放疗组和光子放疗组放疗后对Lym总数存在明显差异(P = 0.04),质子放疗组Lym高于光子放疗组。CD3+ T细胞、CD19+ B细胞、抑制/细胞毒性T细胞CD8、辅助/诱导性T细胞CD4和CD16+ CD56 NK细胞数无差异。结论:放疗靶区体积与Lym变化无明显相关,质子放疗能减轻淋巴细胞的下降。Objective: Exploring the effects of radiotherapy volume and different radiotherapy techniques on the distribution of lymphocytes and their subsets in chest tumors. Method: Select patients with chest malignant tumors undergoing radiotherapy in our department, measure the volume of the target area, calculate the difference in lymphocytes before and after radiotherapy (ΔLym), and conduct correlation analysis. Compare the distribution of Lym and its subgroups after treatment between photon radiotherapy group and proton radiotherapy group. Result: There is no significant correlation observed between ΔLym and target volume through scatter plot analysis. Pearson correlation analysis r = 0.079, P = 0.672. There was a significant difference in the total number of Lym between the proton radiotherapy group and the photon radiotherapy group after radiotherapy (P = 0.04), with the proton radiotherapy group having a higher Lym count than the photon radiotherapy group. There was no difference in the number of CD3+ T cells, CD19+ B cells, CD8 inhibitory/cytotoxic T cells, CD4 helper/inducible T cells, and CD16+ CD56 NK cells. Conclusion: There is no significant correlation between the volume of the radiotherapy target area and
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:216.73.216.90