介孔分子筛MCM-41固载磷钨酸催化苯并三氮唑与查尔酮的氮杂迈克加成反应研究  

Aza-Michael Addition of Chalcone with Benzotriazole Catalyzed by MCM-41 Immobilized H3PW12O40

作　　者：杨敬辉 邢刘庄 谢绍雷[1] 邢雪建 侯亚东 吴阳[1] 惠永海[1] 

机构地区：[1]新疆大学化学化工学院,新疆乌鲁木齐

出　　处：《有机化学研究》2017年第2期107-113,共7页Journal of Organic Chemistry Research

基　　金：国家自然科学基金(Nos. 21362036, 21161026)。

摘　　要：以介孔分子筛MCM-41固载磷钨酸为催化剂,对苯并三氮唑与查尔酮进行了氮杂迈克加成的催化研究。经过条件筛选,发现MCM-41中的磷钨酸负载量对该反应体系有很大的影响,其中50 wt%的磷钨酸负载量更有利于反应的进行,产率可达98%。通过NMR对产物结构进行了表征,并且催化剂具有一定的回收再利用效果。In this paper, mesoporous siliceous material MCM-41 supported H3PW12O40 (PW) could act as an efficient catalyst for the aza-Michael addition reaction of chalcone with benzotriazole. As can be seen from a serial of reaction conditions, the ratio of PW and MCM-41 plays a critical role in the reaction, and the best catalyzed result was achieved when using 50 wt% PW/MCM-41, and the yield was up to 98%. All the products were confirmed by NMR techniques. Moreover, the catalyst was also found to exhibit better recyclability.

关 键 词：MCM-41 磷钨酸 苯并三氮唑 查尔酮 迈克加成 

分 类 号：O64[理学—物理化学]