磺酰氟合成研究进展  

Progress in Synthesis of Sulfonyl Fluoride

作　　者：张国聪 杜雷星 

机构地区：[1]浙江师范大学,化学与生命科学学院,浙江 金华

出　　处：《有机化学研究》2023年第4期268-284,共17页Journal of Organic Chemistry Research

摘　　要：由于磺酰氟基团在有机合成、材料化学和材料科学相关的应用中起到重要作用,将磺酰氟基团选择性地引入到有机分子中已成为一个快速发展的领域,磺酰氟可进行六价硫氟交换反应以及可以利用磺酰基合成氨基酸的生物电子等排体,因此人们开发多种合成磺酰氟的方法,本文介绍了目前已知的合成磺酰氟的方法,包括亲核取代,卤原子交换,氧化,自由基偶联,自由基加成。Because sulfonyl fluorine groups play an important role in organic synthesis, material chemistry and material science, the selective introduction of sulfonyl fluorine groups into organic molecules has become a rapidly developing field. Sulfonyl fluorine can carry out hexavalent sulfur-fluorine exchange reactions and bioelectronic isobars of amino acids can be synthesized by the sulfonyl group. Therefore, a variety of methods for the synthesis of sulfonyl fluorine have been developed. In this paper, the known methods for the synthesis of sulfonyl fluorine are introduced, including nucleophilic substitution, halogen atom exchange, oxidation, free radical coupling and radical addition.

关 键 词：磺酰氟 卤原子交换 含硫衍生物 

分 类 号：G63[文化科学—教育学]