药物治疗胶质瘤相关机制研究进展  

Research Progress of Related Mechanisms about Treatment of Glioma by Medicine

作　　者：张莹莹 童玥[1] 

机构地区：[1]中国药科大学生命科学与技术学院,江苏 南京

出　　处：《药物资讯》2020年第2期78-84,共7页Pharmacy Information

摘　　要：胶质瘤恶性程度高,容易侵袭和转移,手术治疗、放射疗法和药物治疗是目前最常用的治疗方式,而由于胶质瘤易侵袭,病灶与周围正常组织边界不清晰,手术治疗很难将肿瘤病灶完全清除,放射疗法对身体伤害大,成本高,因此药物辅助治疗就显得尤为重要。目前,研究中或已上市的针对胶质瘤的化疗药物或单抗类药物繁多,作用的靶点也不甚相同,本文就药物治疗胶质瘤最新的相关机制进行了综述。High degree of malignancy and easy to invade and metastasize are the characteristics of glioma, and the common methods used to treat glioma are surgery, radiation therapy, and medication now. The first treatment is difficult to completely remove lesions, because the boundary between tumor and surrounding normal tissues is not clear. The second therapy is harmful and costly. So medical treatment is particularly important. At present, there are many chemotherapeutic drugs or mono-clonal antibodies with different mechanisms of action in the research or market. This article summarizes the latest relevant mechanisms of drug treatment for glioma.

关 键 词：肿瘤侵袭 胶质瘤 肿瘤抑制剂 

分 类 号：R73[医药卫生—肿瘤]