基于生存分析的口腔鳞状细胞癌患者研究  

Oral Squamous Cell Carcinoma Patient Study Based on Survival Analysis

作　　者：曾莎 李超 瞿颖秋 张晓良 

机构地区：[1]重庆理工大学理学院,重庆

出　　处：《统计学与应用》2021年第5期794-804,共11页Statistical and Application

摘　　要：本文基于生存分析方法对口腔鳞状细胞癌患者特点及预后影响因素研究。首先利用参数估计和非参数估计对生存函数进行估计,了解其特点;然后基于COX模型,以死亡时间为因变量,分别以年龄、肿瘤阶段及性别为因变量建模,分析生存时间影响因素。研究结果表明将死亡的时间和年龄、肿瘤阶段以及性别建立的模型有效,得出影响口腔鳞状细胞癌患者死亡时间的主要因素为年龄、肿瘤阶段以及性别。Based on the survival analysis method, the characteristics and prognostic factors of patients with oral squamous cell carcinoma were studied. Firstly, the survival function is estimated by parametric estimation and nonparametric estimation to understand its characteristics. Then, based on COX model, time of death was used as the dependent variable, and age, tumor stage and gender were used as the dependent variable to analyze the factors affecting survival time. The results showed that the model of time of death and age, tumor stage and gender was effective, and the main factors influencing the time of death of patients with oral squamous cell carcinoma were age, tumor stage and gender.

关 键 词：参数估计 非参数估计 COX模型 生存分析 

分 类 号：R73[医药卫生—肿瘤]