中医药干预中晚期PLC肝动脉灌注化疗术后恶心呕吐的研究进展  

Research Progress of TCM Intervention on Nausea and Vomiting after PLC Hepatic Arterial Perfusion Chemotherapy

作　　者：许娟娟 唐伟国 付星开 刘源[2] 

机构地区：[1]成都中医药大学中西医结合临床医学院,四川 成都 [2]成都中医药大学附属医院,肿瘤介入科,四川 成都

出　　处：《中医学》2024年第11期3022-3026,共5页Traditional Chinese Medicine

摘　　要：原发性肝癌(Primary Liver Cancer, PLC)因其发病隐匿,大部分患者确诊时已经处于中晚期。近年来随着介入治疗的发展,肝动脉持续性灌注化疗(Hepatic Artery Infusion Chemotherapy, HAIC)越来越受到国内关注并逐渐成为中晚期PLC的重要治疗方案。但HAIC术后仍会出现较多不良反应,其中胃肠道症状最为常见。临床观察发现中医药干预能加速恢复胃肠道功能,对减轻HAIC术后胃肠道反应具有潜在作用优势。本综述主要阐述中医药改善HAIC术后胃肠道反应的治疗现状,有望为中晚期PLC HAIC术后胃肠道反应的防治提供新思路与新方法。Primary liver cancer (PLC) is a common gastrointestinal tumor worldwide. Limited by the characteristics of hidden onset, PLC is mostly diagnosed in the middle and late stages, and chemotherapy, targeted therapy and immunotherapy are the main treatment methods. Studies have shown that hepatic arterial infusion chemotherapy (HAIC) has advantages of better efficacy and less toxic side effects compared with intravenous chemotherapy, and has become an important treatment program for PLC in the middle and late stages. However, there are still many adverse reactions after HAIC, among which gastrointestinal symptoms are the most common. Clinical observation shows that Chinese medicine intervention can accelerate the recovery of gastrointestinal function and has potential advantages in alleviating gastrointestinal reaction after HAIC operation. This review mainly describes the current situation and prospect of improving gastrointestinal reactions after HAIC with traditional Chinese medicine, which is expected to provide new ideas and new methods for the prevention and treatment of gastrointestinal reactions after PLC HAIC.

关 键 词：原发性肝癌 肝动脉灌注化疗 静脉化疗 胃肠道不良反应 中医药 

分 类 号：R73[医药卫生—肿瘤]