中药预防结肠癌的研究进展  

Research Progress of Traditional Chinese Medicine in the Prevention of Colorectal Cancer

作　　者：徐督辉 王威[1,2] 

机构地区：[1]天津中医药大学第一附属医院,天津 [2]国家中医针灸临床医学研究中心,天津

出　　处：《中医学》2025年第2期539-546,共8页Traditional Chinese Medicine

摘　　要：结肠癌(CRC)作为消化系统中常见的恶性肿瘤,其发病率和死亡率持续上升,已成为全球健康的重大挑战之一。结肠癌的高发病率和死亡率促使对其预防的深入研究,对结肠癌的早期预防和干预不仅可以有效降低发病率,也能改善患者的生活质量。中医药以其独特的治疗机制展现出显著的潜力,中药通过抑制结肠癌前期病变、调控细胞生长、促进细胞凋亡、改善机体免疫功能以及逆转耐药性等多重机制,发挥了预防结肠癌的作用。此外,研究还表明中药在抑制肿瘤细胞转化和转移方面具有积极效果。本文综述了中药在结肠癌预防中的最新研究进展,并展望了中药与现代医学结合的前景,以期推动中药在结肠癌防治中的应用和研究。Colorectal cancer (CRC), as a common malignant tumor in the digestive system, has a continuously rising incidence and mortality rate, becoming one of the significant challenges to global health. The high morbidity and mortality of colorectal cancer have prompted in-depth research on its prevention. Early prevention and intervention of colorectal cancer can not only effectively reduce the incidence but also improve the quality of life of patients. Traditional Chinese medicine (TCM) has shown significant potential with its unique therapeutic mechanisms. Chinese herbal medicine plays a role in preventing colorectal cancer through multiple mechanisms, including inhibiting precancerous lesions, regulating cell growth, promoting cell apoptosis, improving immune function, and reversing drug resistance. Additionally, studies have shown that Chinese herbal medicine has positive effects in inhibiting tumor cell transformation and metastasis. This article reviews the latest research progress of Chinese herbal medicine in the prevention of colorectal cancer and looks forward to the prospects of combining Chinese medicine with modern medicine, aiming to promote the application and research of Chinese herbal medicine in t

关 键 词：中药预防 结肠癌 免疫调节 细胞凋亡 耐药机制 

分 类 号：R73[医药卫生—肿瘤]