皮肤Merkel细胞癌放射治疗1例  

A Case of Merkel Cell Carcinoma of the Skin Treated with Radiotherapy

作　　者：訾萌萌 吴春涛 吴庆 许雅贤 张祎 

机构地区：[1]华北理工大学临床医学院,河北 唐山 [2]华北理工大学附属医院肿瘤外科,河北 唐山

出　　处：《世界肿瘤研究》2023年第4期139-143,共5页World Journal of Cancer Research

摘　　要：目的:探讨Merkel细胞癌镜下特点、临床表现、诊断和鉴别诊断、治疗方案、影响预后的因素。方法:对收治的1例Merkel细胞癌临床表现、治疗方案进行分析,并复习相关文献。结果:本病例考虑患者高龄,手术创伤较大,风险较高,选择放射治疗,该患者避免了术后疼痛,未发生并发症。结论:Merkel细胞癌是一种高度恶性的皮肤原发性神经内分泌癌,预后较差,对于可疑患者应尽早明确诊断并积极治疗,具体治疗方案依患者自身情况及病情而定。Objective: To investigate the microscopic features, clinical manifestations, diagnosis and differential diagnosis, treatment options, and factors affecting prognosis of Merkel cell carcinoma. Methods: The clinical manifestations and treatment options of one case of Merkel cell carcinoma admitted were analyzed, and the relevant literature was reviewed. Results: In this case, considering the advanced age of the patient, the surgery was more traumatic and risky, radiation therapy was chosen, and this patient avoided postoperative pain without complications. Conclusion: Merkel cell carcinoma is a highly malignant primary neuroendocrine carcinoma of the skin with a poor prognosis, and suspicious patients should be clearly diagnosed and actively treated as early as possible, and the specific treatment plan depends on the patient’s own situation and condition.

关 键 词：MERKEL细胞癌 放射治疗 免疫组织化学 

分 类 号：R73[医药卫生—肿瘤]