Pregnancy and Obstetrical Outcomes Following Treatment for Cervical Intra-Epithelial Neoplasia (CIN) in Two Hospitals of a Low-Resource Country  

作　　者：Bruno Kenfack Clovis-Achille Tanekeu Atem Bethel Ajong Zabdielle Blonde Goufack Kenfack Patrick Petignat Pierre Marie Tebeu Bruno Kenfack;Clovis-Achille Tanekeu;Atem Bethel Ajong;Zabdielle Blonde Goufack Kenfack;Patrick Petignat;Pierre Marie Tebeu(Department of Gynecology and Obstetrics, Faculty of Medicine and Pharmaceutical Science, University of Dschang, Dschang, Camer-on;Institur Supérieur des Sciences de la Santé, Université des Montagnes, Bangangté, Cameroon;Kekem MD, District Hospital, West Region, Cameroon;Department of Epidemiology and Public Health, Faculty of Medicine and Pharmaceutical Science, University of Dschang, Dschang, Cameron;Geneva University Hospitals, Genevas, Switzerland;Faculty of Medicine and Biomedical Science, University of Yaounde I, Yaounde, Cameroon)

机构地区：[1]Department of Gynecology and Obstetrics, Faculty of Medicine and Pharmaceutical Science, University of Dschang, Dschang, Camer-on [2]Institur Supérieur des Sciences de la Santé, Université des Montagnes, Bangangté, Cameroon [3]Kekem MD, District Hospital, West Region, Cameroon [4]Department of Epidemiology and Public Health, Faculty of Medicine and Pharmaceutical Science, University of Dschang, Dschang, Cameron [5]Geneva University Hospitals, Genevas, Switzerland [6]Faculty of Medicine and Biomedical Science, University of Yaounde I, Yaounde, Cameroon

出　　处：《Advances in Reproductive Sciences》2024年第1期51-59,共9页生殖科学（英文）

摘　　要：Objective: In Cameroon, more than 80% of women suffering from cervical intraepithelial neoplasia (CIN) are within the reproductive age. This study intended to analyze the pregnancy outcomes following cervical treatment in Cameroon. Methods: This was a cohort study with two years retrospective data collection involving 82 women who underwent cervical treatment for CIN in two Cameroonian hospitals from January 2015 to December 2017. Data were collected from CIN treatment to end of pregnancy where applicable. Data analysis was done using Epi Info software version 3.5.4. Results: We collected data from 82 patients aged 27 to 48 years, with a mean age of 36.5 (SD: 5.3) years. During the study period, 33 out of 82 participants became pregnant 40.2 [29.56 - 51.66]%. The factor associated with pregnancy occurrence after treatment was age less than 35 years (Odds ratio = 4.37 [1.7 - 11.2]. From the 33 pregnancies recorded, 17 (51.5%) ended in a delivery, amongst which 15 (88.2%) were vaginal. Conclusion: Pregnancy frequency over two years following cervical treatment for CIN was relatively good, and younger women (age 35 years) were significantly more like to have conceived compared to their older counterparts. Post-treatment delivery outcomes seem to be similar to those in the general population.Objective: In Cameroon, more than 80% of women suffering from cervical intraepithelial neoplasia (CIN) are within the reproductive age. This study intended to analyze the pregnancy outcomes following cervical treatment in Cameroon. Methods: This was a cohort study with two years retrospective data collection involving 82 women who underwent cervical treatment for CIN in two Cameroonian hospitals from January 2015 to December 2017. Data were collected from CIN treatment to end of pregnancy where applicable. Data analysis was done using Epi Info software version 3.5.4. Results: We collected data from 82 patients aged 27 to 48 years, with a mean age of 36.5 (SD: 5.3) years. During the study period, 33 out of 82 participants became pregnant 40.2 [29.56 - 51.66]%. The factor associated with pregnancy occurrence after treatment was age less than 35 years (Odds ratio = 4.37 [1.7 - 11.2]. From the 33 pregnancies recorded, 17 (51.5%) ended in a delivery, amongst which 15 (88.2%) were vaginal. Conclusion: Pregnancy frequency over two years following cervical treatment for CIN was relatively good, and younger women (age 35 years) were significantly more like to have conceived compared to their older counterparts. Post-treatment delivery outcomes seem to be similar to those in the general population.

关 键 词：Cervical Intraepithelial Neoplasia Cervical Treatment Pregnancy Outcome 

分 类 号：R73[医药卫生—肿瘤]