Efficacy of deferasirox for the treatment of iron overload in a child affected by Juvenile Hemochromatosis  

作　　者：Nicoletta Masera Alessandro Cattoni Valentina Decimi Valeria D’Apolito Cristina Arosio Raffaella Mariani Alberto Piperno 

机构地区：[1]Consortium for Human Molecular Genetics, Monza, Italy [2]Department of Health Sciences, University of Milano-Bicocca, Ospedale S. Gerardo, Monza, Italy [3]Department of Pediatrics, University of Milano-Bicocca, Ospedale S. Gerardo, Monza, Italy

出　　处：《Case Reports in Clinical Medicine》2013年第2期126-128,共3页临床医学病理报告（英文）

摘　　要：We report the case of a 7 years old girl with Juvenile Hemochromatosis, due to homozygous mutation of HJV, which had increased serum iron indices and liver iron overload in the absence of any clinical sign of disease. Oral iron chelation with low dose deferasirox showed good efficacy and no side effects. The oral iron chelator deferasirox could be a valid option for removing excess iron in early Juvenile Hemochromatosis.We report the case of a 7 years old girl with Juvenile Hemochromatosis, due to homozygous mutation of HJV, which had increased serum iron indices and liver iron overload in the absence of any clinical sign of disease. Oral iron chelation with low dose deferasirox showed good efficacy and no side effects. The oral iron chelator deferasirox could be a valid option for removing excess iron in early Juvenile Hemochromatosis.

关 键 词：JUVENILE HEMOCHROMATOSIS DEFERASIROX IRON CHELATION CHILD IRON Overload 

分 类 号：R5[医药卫生—内科学]