Localized Administration of Tissue Plasminogen Activator through the Ophthalmic Artery in the Setting of Central Retinal Artery Occlusion  

作　　者：Deanna Ingrassia Miano Gilbert Xue Erika White Faisal Ridha Al-Timimi Deanna Ingrassia Miano;Gilbert Xue;Erika White;Faisal Ridha Al-Timimi(Ascension Eye Institute, Ascension Macomb-Oakland Hospital, Warren, Michigan, USA;Kresge Eye Institute, Wayne State University, Detroit, Michigan, USA)

机构地区：[1]Ascension Eye Institute, Ascension Macomb-Oakland Hospital, Warren, Michigan, USA [2]Kresge Eye Institute, Wayne State University, Detroit, Michigan, USA

出　　处：《Case Reports in Clinical Medicine》2022年第5期152-159,共8页临床医学病理报告（英文）

摘　　要：Treatment of central retinal artery occlusion (CRAO) has been an ambiguous entity in the medical community. Many interventions have been explored;however, a standard of care has yet to be defined. Recent studies have suggested localized intra-arterial fibrinolysis as a promising method;however, a timeframe for optimal treatment initiation continues to be investigated. This case demonstrates an instance of CRAO treated with local fibrinolysis, however, what could be due to delayed time-to-treat, final visual outcomes were unfavorable. In conjunction with supporting literature, we believe optimization of thrombolytic protocols should be sought after to facilitate successful treatment outcomes. In addition, we encourage community awareness of the signs and symptoms of CRAO in hopes that earlier patient presentations will lead to swifter interventions and overall preservation of ocular function.Treatment of central retinal artery occlusion (CRAO) has been an ambiguous entity in the medical community. Many interventions have been explored;however, a standard of care has yet to be defined. Recent studies have suggested localized intra-arterial fibrinolysis as a promising method;however, a timeframe for optimal treatment initiation continues to be investigated. This case demonstrates an instance of CRAO treated with local fibrinolysis, however, what could be due to delayed time-to-treat, final visual outcomes were unfavorable. In conjunction with supporting literature, we believe optimization of thrombolytic protocols should be sought after to facilitate successful treatment outcomes. In addition, we encourage community awareness of the signs and symptoms of CRAO in hopes that earlier patient presentations will lead to swifter interventions and overall preservation of ocular function.

关 键 词：Central Retinal Artery Occlusion OPHTHALMOLOGY Neuroendovascular Localized Intra-Arterial Fibrinolysis 

分 类 号：R73[医药卫生—肿瘤]