Clinical Value of Platelet-Related Parameters and Monocyte Counts in Patients with Oculomotor Myasthenia Gravis  

作　　者：Yaping Sun Xianglin Cheng Ke Peng Yaping Sun;Xianglin Cheng;Ke Peng(Department of Neurology, The First Affiliated Hospital of Yangtze University, Jingzhou, China)

机构地区：[1]Department of Neurology, The First Affiliated Hospital of Yangtze University, Jingzhou, China

出　　处：《Case Reports in Clinical Medicine》2024年第12期572-580,共9页临床医学病理报告(英文)

摘　　要：Background: Our study aimed to investigate the clinical value of platelet parameters and the number of Monocytes (MONO) in the peripheral blood of patients with Ocular Myasthenia Gravis (OMG). Methods: Fifty patients discharged from the Department of Neurology of the First People’s Hospital of Jingzhou City with the diagnosis of OMG from January 1, 2020, to December 31, 2023, were selected as the experimental group, and healthy medical examiners were selected as the control group during the same period. The differences in peripheral blood mononuclear cell count and platelet-related parameters between the two groups were compared. ROC curves were drawn to analyze the clinical value of the studied indexes in patients with OMG. Results: Patients with OMG had significantly higher monocyte counts and narrower platelet distributions compared with normal adults;further logistic regression analysis revealed that higher monocyte counts and narrower Platelet Distribution Width (PDW) may be independent influences on the occurrence of OMG (p Conclusion: Peripheral blood mononuclear cell count and PDW have some diagnostic value in OMG.Background: Our study aimed to investigate the clinical value of platelet parameters and the number of Monocytes (MONO) in the peripheral blood of patients with Ocular Myasthenia Gravis (OMG). Methods: Fifty patients discharged from the Department of Neurology of the First People’s Hospital of Jingzhou City with the diagnosis of OMG from January 1, 2020, to December 31, 2023, were selected as the experimental group, and healthy medical examiners were selected as the control group during the same period. The differences in peripheral blood mononuclear cell count and platelet-related parameters between the two groups were compared. ROC curves were drawn to analyze the clinical value of the studied indexes in patients with OMG. Results: Patients with OMG had significantly higher monocyte counts and narrower platelet distributions compared with normal adults;further logistic regression analysis revealed that higher monocyte counts and narrower Platelet Distribution Width (PDW) may be independent influences on the occurrence of OMG (p Conclusion: Peripheral blood mononuclear cell count and PDW have some diagnostic value in OMG.

关 键 词：Ocular Myasthenia Gravis Mononuclear Cell Platelet Distribution Width 

分 类 号：R73[医药卫生—肿瘤]