Kikuchi-Fujimoto Disease Mimicking Tuberculosis  

Kikuchi-Fujimoto Disease Mimicking Tuberculosis

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作  者:Madiha Mahfoudhi Imen Gorsane Sami Turki Taieb Ben Abdallah 

机构地区:[1]Department of Internal Medicine A, Charles Nicolle Hospital, Tunis, Tunisia

出  处:《International Journal of Clinical Medicine》2015年第10期725-728,共4页临床医学国际期刊(英文)

摘  要:A 32-year-old woman presented with a fever and cervical lymphadenopathies. The research for Mycobacterium tuberculosis was negative. Tuberculin skin test was positive. Laboratory investigations showed an elevated erythrocyte sedimentation rate and a normal white blood cell count. Bacteriological and viral investigations were negative. Quantiferon-Tb Gold test was indeterminate. Thraco-abdominal and pelvic computed tomography, FDG-PET and gallium scintigraphy revealed no abnormalities. Histological study of cervical lymph node biopsy found signs in favor of histiocytic necrotizing lymphadenitis. There were no epithelioid cell granulomas. A test tuberculosis treatment was refused by the patient. The evolution was marked by spontaneous clinical and biological resolution in fifty days. The negative Lowenstein-Jensen culture eliminated formally the tuberculosis. KFD was thus the most likely diagnosis.A 32-year-old woman presented with a fever and cervical lymphadenopathies. The research for Mycobacterium tuberculosis was negative. Tuberculin skin test was positive. Laboratory investigations showed an elevated erythrocyte sedimentation rate and a normal white blood cell count. Bacteriological and viral investigations were negative. Quantiferon-Tb Gold test was indeterminate. Thraco-abdominal and pelvic computed tomography, FDG-PET and gallium scintigraphy revealed no abnormalities. Histological study of cervical lymph node biopsy found signs in favor of histiocytic necrotizing lymphadenitis. There were no epithelioid cell granulomas. A test tuberculosis treatment was refused by the patient. The evolution was marked by spontaneous clinical and biological resolution in fifty days. The negative Lowenstein-Jensen culture eliminated formally the tuberculosis. KFD was thus the most likely diagnosis.

关 键 词:Kikuchi-Fujimoto DISEASE MYCOBACTERIUM TUBERCULOSIS LYMPHADENITIS HISTOLOGY 

分 类 号:R5[医药卫生—内科学]

 

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