The Transcutaneous Vagus Nerve Stimulation Output of the NuCalm Device of Solace Lifesciences Is Found to Be a Multifractal and Therefore It Is Indicated in the Treatment of Heart Rate Variability in the Dysfunction of Autonomic Nervous System in Anxiety, Depression and Stress  

作　　者：Sergio Conte Fang Wang Nicoletta Sala Francesco Losito Casciaro Franco Orsucci Giuseppe Serafini Ferda Kaleagasioglu Leonardo Mendolicchio Rich Norman Elio Conte 

机构地区：[1]School of Advanced International Studies on Applied Theoretical and Non Linear Methodologies of Physics, Bari, Italy [2]College of Science/Agricultural Mathematical Modeling and Data Processing Center, Hunan Agricultural University, Changsha, China [3]University of Lugano, ISSI/Cerfim, Lugano, Swizerland [4]Department of Biomedical Sciences and Human Oncology, University of Bari, Bari, Italy [5]Division of Psychology, University College, London, England [6]Tor Vergata University, Rome, Italy [7]Faculty of Medicine, Near East University, North Nicosia, Turkish Republic of Northern Cyprus [8]Clinic Villa Miralago, ASL Varese, Italy

出　　处：《Journal of Behavioral and Brain Science》2017年第11期532-543,共12页行为与脑科学期刊（英文）

摘　　要：We have investigated the Nu Calm Transcutaneous Vagus Nerve Stimulation device of the NuCalm Solace Lifesciences founding that it gives a multifractal output. A diminishing fractal/multifractal HRV is consistently reported in literature as related to a serious Autonomic Nervous System (ANS) dysfunction that of course we observe in several psychological and psychiatric disorders. Therefore, we suggest the investigators to apply such a device in subjects affected from anxiety, depression and stress using the method of inducing tVNS stimulation.We have investigated the Nu Calm Transcutaneous Vagus Nerve Stimulation device of the NuCalm Solace Lifesciences founding that it gives a multifractal output. A diminishing fractal/multifractal HRV is consistently reported in literature as related to a serious Autonomic Nervous System (ANS) dysfunction that of course we observe in several psychological and psychiatric disorders. Therefore, we suggest the investigators to apply such a device in subjects affected from anxiety, depression and stress using the method of inducing tVNS stimulation.

关 键 词：DEPRESSION ANXIETY STRESS TRANSCUTANEOUS Vagus Nerve Stimulation Neuromodulation Heart Rate Variablity MULTIFRACTALS 

分 类 号：R74[医药卫生—神经病学与精神病学]