Age- and Gender-Specific Changes in Thyroid Size and Thyroid Function Test Values of Euthyroid Subjects  

作　　者：Tika Ram Lamichhane Sandeep Prashad Pant Binod Lamichhane Chhabindra Gautam Sharma Paudel Binod Kumar Yadav Hari Prasad Lamichhane 

机构地区：[1]Central Department of Physics, Tribhuvan University, Kathmandu, Nepal [2]Department of Radiology & Imaging, Tribhuvan University Teaching Hospital, Kathmandu, Nepal [3]Department of Biochemistry, Tribhuvan University Teaching Hospital, Kathmandu, Nepal

出　　处：《Journal of Biosciences and Medicines》2018年第11期59-73,共15页生物科学与医学（英文）

摘　　要：Background: The thyroid status is evaluated by two clinical diagnostic tests which are thyroid ultrasonography and thyroid function tests. The objective of this research is to critically analyze the age and gender based variations of thyroid volume and thyroid hormone levels in the hospital based euthyroid subjects. Methodology: A total of 221 euthyroid subjects aged 1 - 86 years were selected to observe the normal thyroid size by ultrasonography at Department of Radiology and the thyroid function test values (FT3, FT4 and TSH) of 2413 euthyroid subjects aged (Results: The best fitted equations with significant correlation coefficients and p Conclusion: The thyroid size first increases and then decreases whereas the thyroxin level first decreases and then increases with aging. Left lobe volume is almost same for both genders and right lobe volume is higher in males. The thyroid size in menarche and menopause periods of females is larger than that of males. Such age- and gender-specific changes recommend the new refer-ence ranges for the normal thyroid functions.Background: The thyroid status is evaluated by two clinical diagnostic tests which are thyroid ultrasonography and thyroid function tests. The objective of this research is to critically analyze the age and gender based variations of thyroid volume and thyroid hormone levels in the hospital based euthyroid subjects. Methodology: A total of 221 euthyroid subjects aged 1 - 86 years were selected to observe the normal thyroid size by ultrasonography at Department of Radiology and the thyroid function test values (FT3, FT4 and TSH) of 2413 euthyroid subjects aged (Results: The best fitted equations with significant correlation coefficients and p Conclusion: The thyroid size first increases and then decreases whereas the thyroxin level first decreases and then increases with aging. Left lobe volume is almost same for both genders and right lobe volume is higher in males. The thyroid size in menarche and menopause periods of females is larger than that of males. Such age- and gender-specific changes recommend the new refer-ence ranges for the normal thyroid functions.

关 键 词：Euthyroid Subject THYROID Function Test THYROID HORMONE Levels THYROID ULTRASONOGRAPHY Empirical Relation 

分 类 号：R5[医药卫生—内科学]