Feasibility of Performing Sentinel Lymph Node Biopsy (SLNB) after Mastectomy: A Case Report  

作　　者：Hanadi Bu-Ali Eleftherios P. Mamouna 

机构地区：[1]Aultman Cancer Center, Canton, OH and Akron General Medical Center, Akron, USA [2]Aultman Cancer Center, Canton, OH and Northeastern Ohio Universities College of Medicine, Rootstown, USA

出　　处：《Journal of Cancer Therapy》2010年第2期91-93,共3页癌症治疗（英文）

摘　　要：Introduction: Previous mastectomy remains a contraindication to SLNB as normal drainage patterns of the breast can be disturbed. Patients diagnosed with DCIS on core biopsy and later found to have microinvasive or invasive carci-noma at the time of mastectomy are deprived of the opportunity for SLNB and need to undergo axillary dissection. We explored the option and feasibility of performing SLNB in a 39-year-old female who underwent a simple mastectomy without axillary sampling for extensive DCIS and later found to have microinvasive ductal carcinoma on permanent pathology. Results: Lymphatic mapping using subdermal injection of 99mTc-labeled sulfur colloid and blue dye led to the identification of five SLNs. Histopathologic examination showed no metastasis. Conclusion: SNLB is feasible in this setting. However, before its use is routinely adopted, its feasibility and accuracy has to be demonstrated in larger num-bers of patients in whom a negative SLNB is followed by a completion axillary dissection.Introduction: Previous mastectomy remains a contraindication to SLNB as normal drainage patterns of the breast can be disturbed. Patients diagnosed with DCIS on core biopsy and later found to have microinvasive or invasive carci-noma at the time of mastectomy are deprived of the opportunity for SLNB and need to undergo axillary dissection. We explored the option and feasibility of performing SLNB in a 39-year-old female who underwent a simple mastectomy without axillary sampling for extensive DCIS and later found to have microinvasive ductal carcinoma on permanent pathology. Results: Lymphatic mapping using subdermal injection of 99mTc-labeled sulfur colloid and blue dye led to the identification of five SLNs. Histopathologic examination showed no metastasis. Conclusion: SNLB is feasible in this setting. However, before its use is routinely adopted, its feasibility and accuracy has to be demonstrated in larger num-bers of patients in whom a negative SLNB is followed by a completion axillary dissection.

关 键 词：Sentinel LYMPH NODE Biopsy Lymphatic Mapping MASTECTOMY LYMPHOSCINTIGRAPHY AXILLARY LYMPH NODE Dissection 

分 类 号：R73[医药卫生—肿瘤]