Microangiopathic Hemolytic Anemia and Diffuse Bone Metastasis by Signet Ring Cell Adenocarcinoma  

作　　者：Andres JMunoz Martin Pilar Garcia Alfonso Maria Carmen Riesco Martinez Virginia Martinez Marin Yolanda Jerez Gilarranz Rebeca Mondejar Solis Miguel Martin Jimenez 

机构地区：[1]Medical Oncology Service,Hospital General Universitario“Gregorio Maranon”,Madrid,Spain.

出　　处：《Journal of Cancer Therapy》2010年第2期94-96,共3页癌症治疗（英文）

摘　　要：Microangiopathic hemolytic anemia (MAHA) is a rare paraneoplastic syndrome and is typically associated with gastric adenocarcinoma. We report a 47-year-old woman who presented with asthenia, lower back pain and bleeding. Twelve years ago the patient underwent total gastrectomy due to gastric adenocarcinoma and achieved complete remission. The patient was diagnosed with MAHA and diffuses bone metastasis of signet ring cell adenocarcinoma of unknown origin and was treated successfully with polichemotherapy based on cisplatin and 5-fluorouracil.Microangiopathic hemolytic anemia (MAHA) is a rare paraneoplastic syndrome and is typically associated with gastric adenocarcinoma. We report a 47-year-old woman who presented with asthenia, lower back pain and bleeding. Twelve years ago the patient underwent total gastrectomy due to gastric adenocarcinoma and achieved complete remission. The patient was diagnosed with MAHA and diffuses bone metastasis of signet ring cell adenocarcinoma of unknown origin and was treated successfully with polichemotherapy based on cisplatin and 5-fluorouracil.x

关 键 词：Microangiopathic Haemolytic Anemia Gastric Cancer Paraneoplastic Syndrome CHEMOTHERAPY Signet Ring Cell Adenocarcinoma 

分 类 号：R73[医药卫生—肿瘤]