Cancers in Children Ages 8 to 12 Are Injury-Related  

作　　者：Kirsten H. Walen 

机构地区：[1]CROMOS, Richmond, USA

出　　处：《Journal of Cancer Therapy》2015年第2期177-181,共5页癌症治疗（英文）

摘　　要：Cancers in young children in early growing age was a short PBS (KQED) report (11/21/2014), but without informational source, which prompted a Google search. Sports-associated injuries with medical healing treatments concluded that there were no association between these body traumas and cancer development. But there are other activities from young children, such as “dare-devil” skateboard and bicycling meter-high jumping with potential high energy falls, to serious broken-bone injuries. Falls of children are among the most common causes of US emergency response. The question is why bodily injury is associated with cancer-development? An answer to this question was exemplified by osteosarcoma in young children, which suggested that injury to growing points of bone and surrounding soft tissue cells would elicit a repair process (wound healing process) producing polyploidy with diplochromosomes. The non-mitotic reductive division of such 4-chromatid chromosomes has been shown?in vitro?to produce pathological cancer-like phenotypes, including gain of a proliferative advantage.Cancers in young children in early growing age was a short PBS (KQED) report (11/21/2014), but without informational source, which prompted a Google search. Sports-associated injuries with medical healing treatments concluded that there were no association between these body traumas and cancer development. But there are other activities from young children, such as “dare-devil” skateboard and bicycling meter-high jumping with potential high energy falls, to serious broken-bone injuries. Falls of children are among the most common causes of US emergency response. The question is why bodily injury is associated with cancer-development? An answer to this question was exemplified by osteosarcoma in young children, which suggested that injury to growing points of bone and surrounding soft tissue cells would elicit a repair process (wound healing process) producing polyploidy with diplochromosomes. The non-mitotic reductive division of such 4-chromatid chromosomes has been shown?in vitro?to produce pathological cancer-like phenotypes, including gain of a proliferative advantage.

关 键 词：ENDOMITOSIS Endotetraploidization Diplochromosomes REDUCTIVE Division Genomic Change PROLIFERATIVE ADVANTAGE Wound HEALING 

分 类 号：R73[医药卫生—肿瘤]